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High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)

dc.creatorGarcía, Angelina
dc.creatorDemarchi, Dario
dc.creatorTovo Rodrigues, Luciana
dc.creatorPauro, Maia
dc.creatorCallegari Jacques, Sidia M.
dc.creatorSalzano, Francisco M.
dc.creatorHutz, Mara H.
dc.date2015-07
dc.date.accessioned2021-04-06T18:18:53Z
dc.date.available2021-04-06T18:18:53Z
dc.identifierGarcía, Angelina; Demarchi, Dario; Tovo Rodrigues, Luciana; Pauro, Maia; Callegari Jacques, Sidia M.; et al.; High interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs); Sociedade Brasileira de Genética; Genetics And Molecular Biology; 38; 3; 7-2015; 324-331
dc.identifier1415-4757
dc.identifierhttp://hdl.handle.net/11336/11103
dc.identifier1678-4685
dc.identifier.urihttp://suquia.ffyh.unc.edu.ar/handle/11336/11103
dc.descriptionThe population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions. The AIM estimates indicated a greater influence of the Native American ancestry as compared to previous studies in the same or other Argentinean regions, but smaller than that observed with the mtDNA tests. These differences can be explained, respectively, by different genetic contributions between rural and urban areas, and asymmetric gene flow occurred in the past. But a most unexpected finding was the marked interpopulation genetic homogeneity found in villages located in diverse geographic environments across a wide territory, suggesting considerable gene flow.
dc.descriptionFil: García, Angelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina
dc.descriptionFil: Demarchi, Dario. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina
dc.descriptionFil: Tovo Rodrigues, Luciana. Universidade Federal do Rio Grande do Sul; Brasil
dc.descriptionFil: Pauro, Maia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades; Argentina
dc.descriptionFil: Callegari Jacques, Sidia M.. Universidade Federal do Rio Grande do Sul; Brasil
dc.descriptionFil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; Brasil
dc.descriptionFil: Hutz, Mara H.. Universidade Federal do Rio Grande do Sul; Brasil
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Genética
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.1590/S1415-475738320140260
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://ref.scielo.org/pnsdds
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/26500436/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.subjectAIMs
dc.subjectCÓRDOBA
dc.subjectMIGRATIONS
dc.subjectPOPULATION STRUCTURE
dc.subjectSAN LUIS
dc.subjectOtras Humanidades
dc.subjectOtras Humanidades
dc.subjectHUMANIDADES
dc.subjectOtras Humanidades
dc.subjectOtras Humanidades
dc.subjectHUMANIDADES
dc.titleHigh interpopulation homogeneity in Central Argentina as assessed by Ancestry Informative Markers (AIMs)
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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